Posted by sk85 on July 29, 2014, at 7:13:14
In reply to Re: at 8 weeks, posted by porkpiehat on July 18, 2014, at 17:18:41
> I think I might have to switch back to to Brintellix from Viibryd. Viibryd is much better for my mood and sex drive, but it messes with my sleep and makes me very tired for the second half of the day. I have to take stims to stay awake and now they are making me more and more edgy.
>
> Brintellix had a great impact on cognitive functioning and my sleep was better. I had to add some Celexa to keep me out of the apathetic space.
>
> Does anyone else hate having to make these decisions about which part of their lives they are going to have to sacrifice based on their med choices? Jeez Louise.I can add that Brintellix in my experience does nothing to intefere with sleep. In fact while ago I was dependent on Seroquel/Mirtazapine to get some (at best mediocre quality) sleep while on Zoloft. I'm currently finally off of both of them and sleep like a baby (again this started to appear approx 1,5 months after taking it). Perhaps it's again that opioid normalization that vortioxetine might possess, because a normally functioning brain opioid system is necessary for deep sleep. Anyone who has ever done the low dose naltrexone trial with themselves can attest that once you block opioid receptors you will have the worst sleep ever.
All in all, it appears that Brintellix is a drug that works slowly and needs time to show benefit (!). This is in contrast with Lundbeck's advertising that it works within 1 week. Yes you do get some action during the first week, but this is just a passing thing.
poster:sk85
thread:1065908
URL: http://www.dr-bob.org/babble/20140717/msgs/1068928.html