Posted by SLS on October 20, 2014, at 9:18:00
In reply to Re: need just a bit more, posted by Christ_empowered on October 20, 2014, at 7:25:43
> (thank you, SLS)
I would like to thank you, too. Your contributions here are accurate, creative, intelligent, and kind. You really know your stuff, and I like to steal your ideas for myself.
:-)
I would just add that Remeron is more likely to produce a robust antidepressant effect at dosages of 45 - 75 mg/day. Some people go to 90 mg/day. As you mentioned, sedation and weight gain often subside at higher dosages. Believe it or not, the neuroleptic antipsychotic, lurasidone (Latuda), like Remeron, is a potent antagonist at NE alpha-2 receptors. Along with that is is an agonist of 5-HT7 receptors and a partial agonist at 5-HT1a receptors, Latuda looks good on paper to treat depression. I haven't seen it work for anyone yet. Too few people have tried it. It is not approved for bipolar mania, believe it or not. The drug company has not yet presented clinical data to the FDA, but they plan to do so.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1072534
URL: http://www.dr-bob.org/babble/20141017/msgs/1072547.html