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Re: Your dosing is too low. » seekinginformation

Posted by phidippus on November 26, 2014, at 16:22:08

In reply to Re: Your dosing is too low. » phidippus, posted by seekinginformation on November 24, 2014, at 18:21:02

>low and slow for me.

I'm not saying you won't see results with doses lower than typically used to treat OCD, but right now you're even on the low side for treating depression.

Can I ask why you're going slow and low (except for the the obvious EPS symptoms you seem to be susceptible to)?

>My goal is to get some of that glutamete action before boosting serotonin

Right now the glutamatergic disfunction theory of OCD is in its infancy.

The APA has a cool algorithm for treating OCD and it works kind of like this: serotogenic AD>Atypical Antipsychotic>anti-glutamatergic agent. Boosting an SSRI with Clomipramine is another part of the algorithm. BUT, you're doses need to be adequate. I'd say at least 30 mg on the Prozac and anywhere from 100 mg to 300 mg on the Clomipramine. The Gabapentin can be raised to 2400 mg.

Have you thought of adding an atypical anytypsychotic?

Dopamine tends to be raised in certain areas of the brain of people with ocd, in particular the nucleus accumbens.

BUT, I wouldn't add it until your ADs were at the right dose.

Eric


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