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Re: Starting Cymbalta, how much til it helps pain? » Phillipa

Posted by ed_uk2010 on December 8, 2014, at 3:55:27

In reply to Re: Starting Cymbalta, how much til it helps pain? » ed_uk2010, posted by Phillipa on December 7, 2014, at 18:11:38

> Ed I just don't want any other meds. Taking a 200mg of motrin for a headache once a day is my limit. I am considering tramadol as quite few posters combine it with SSRI? Phillipa

Very low doses of Motrin (such as you take) appear to cause very few side effects. Why would you want to replace it with tramadol?

Ibuprofen, adults...

Occasional doses - usually no side effects. One of the best tolerated NSAIDs overall. YMMV.

200mg up to three times a day - very low incidence of side effects. If taking every day, a gastro-protective med should be considered if at risk eg. over 65. Very low cardiovascular risk at this dose, if any.

400mg up to three times a day - low incidence of side effects but gastro-protective med should be added if taking regularly. Very low cardiovascular risk in the short term, possible small risk in the long term if taken continuously.

High dose ibuprofen eg. 600mg-800mg three or four times a day. Clearly higher incidence of adverse effects than lower dose. Generally suitable for short-term use only under medical advice. Long term use is associated with some cardiovascular risk.

In general, avoid total doses greater than 1200mg per day unless clearly necessary.

......................

Bear in mind that acetaminophen is very safe at the recommended dose. Do not overdose and you will be fine. There is a very big difference between the safety of a med at the recommended dose and its safety in overdose. For acetaminophen the two are entirely unrelated. Therapeutic doses have a very low incidence of side effects, but it is generally a less potent pain reliever than NSAIDs and has no anti-inflammatory effect.

Tramadol has a high incidence of side effects and withdrawal symptoms. Acetaminophen is clearly safer but if it doesn't help you can consider stronger meds.

 

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