Posted by meffect on January 24, 2015, at 21:57:08
In reply to Re: Dopamine increasing drugs, worsen depression » meffect, posted by ed_uk2010 on January 24, 2015, at 14:49:28
> Hi.
>
> >I'm so confused. Depression runs in my family and I seem to have an extreme sensitivity to emotions - since i was born.
>
> OK, are you also diagnosed with depression or something else? Like borderline personality disorder, for example? What sort of illness runs in your family? Severe/recurrent depression... bipolar disorder (manic-depression) etc?
>I've never had a pdoc diagnose me with anything. In my town they dont seem to be interested in diagnosis. They just give drugs. Never taken a test or anything. I've seen 3 pdocs in my town. My moms side of the family has something psychologically wrong but they never got a diagnosis either. My mom takes lexapro. I dont think bipolar -- though I do have high's and lows that can happen very rapidly depending on the situation I put myself in, it doesn't seem like bipolar. Honestly, in my research, borderline personality disorder fits me the most -- except i dont self harm
> >I overact on almost everything. I avoid social situations because I usually end up interpreting someones words, tone, facial expression, etc as negative (even though I tell myself its not) and I end up feeling extremely depressed and I often times end up crying that night and wanting to kill myself. sometimes i wish an accident would happen and kill me because i cant do it myself
>
> Do you feel temporarily OK when things are going better? It sounds like your emotions are very over-reactive to the situation/circumstances. Have you ever had cognitive-behavioural therapy?Yea i feel ok today. I took a higher dose of vybrid. never had cbt. I was having problems with my marriage when I made the original post. good point...
>
> >i have an dependence on benzo's, i feel bored all the time. ssri's help but they make me tired i think
>
> What medication are you taking at the moment? Tell us about the benzo situation... Long-term use of benzos can aggravate depression. I expect you'd do better on an antidepressant alone (assuming you find the right one), an MAOI could potentially be very effective if you could tolerate one and stick to the dietary restrictions. Nardil, for example. MAOIs do often aggravate insomnia unfortunately. As for SSRIs and related antidepressants.... what have you tried? Some tend to cause more tiredness than others.I'm taking 1mg of Klonopin at night for sleep. 30mg of temazepam at night for sleep. 2mg of Xanax which I take only at night if I really have trouble sleeping; and I usually cut it in half first. Actually lately with the Provigil, I will take 1mg of xanax during the day if things get too much to handle. Vybrid 10-20mg daily. I'm trying to go down to 10mg because of the sexual side effects. I've tried every SSRI. Lexapro and Vybrid seem to work the best for calming my emotions, but Lexapro makes me SOOOO tired to the point where I can not avoid taking a 3 hour nap no matter how hard i try. Zoloft and Prozac make me too anxious and irritable. Paxil made me tired like lexapro but i never gave it a good trial run. On Parnate, I had to take a nap at lunch. Parnate felt like a week dexedrine with a crash that = nap. Nardil was better than Parnate but I did not like it; i felt very drugged on it and it felt wrong. The Vybrid is the only ssri that doesnt make me overly tired. It makes me tired, but I can overcome it with provigil or caffeine.
>
> >I'm tired all the time, i take naps at lunch and i have rem sleep and i hardly get any rest.
>
> Do you mean you have vivid dreams?
I have dreams about random things over and over and I never actually seem to fall asleep. I think 1 hour passes but really only 20 minutes passed. It's like im borderline between falling asleep (unconscious) and awake, but having these very weird dreams while trying to get fully asleep. The dreams are very vivid and are usually about current events like work> >im tired all the time so my docs give me stims.
>
> You must be in the US? That's the only place (pretty much) where docs think amphetamines and similar drugs are a sensible solution to fatigue. Clearly, for you, they are not. This is not unusual. In general, it's best to remove the cause of the fatigue where possible. If one antidepressant is making you too tired it would be worth trying another. I understand you've already tried several but I imagine there are still options.Yes, US. I've tried Provigil, Dexedrine Spansules, and Vyvanse. With the dexedrine spansules, i feel amazing. Calm and clear headed and no social anxiety whatsoever. Except, it only lasts about 3 hours. Then the comedown is pretty brutal; i need a benzo. Vyvanse only lasts about 4 hours in my system, same problem as dexedrine. Provigil on the other hand, seems to last all day; which is great. Actually I took 200mg of provigil the day I made my original post, and the comedown from that made me break down :/
> Mild stimulants such as caffeine may be tolerable, assuming that caffeine doesn't worsen your anxiety. You should certainly avoid caffeine in the late afternoon and evening if you suffer from sleep problems.I drink two 16oz rockstar energy drinks and it barely does anything. thats 160mg of caffeine x2 + whatever other stuff is in those drinks. Yea i usually stop drinking caffeine by 2:00pm. I have this weird issue where im tired all day, but as soon as it's time to go to bed, I feel more alert and awake.
> >i cant handle epinephrine increasers, but it seems to cause more anxiety than heightened emotional responses.
>
> Which drugs in particular are you referring to? Wellbutrin?Wellbutrin, i can handle about 75MG SR, but not on a daily basis. Only when I need something to stay awake. Anything higher than that and I feel very anxious and I'm snappy at people. Pristiq was probably the best I've tried for SNRI's, but the anxiety did catch up to me to where I couldnt handle it anymore. Fetzima was very bad from the beginning, i could only handle 3 days on it before i was so anxious I had to stop.
poster:meffect
thread:1075449
URL: http://www.dr-bob.org/babble/20150102/msgs/1075502.html