Posted by Escapee on May 12, 2015, at 10:04:56
In reply to Re: 2 benzos? » phidippus, posted by tony p on May 9, 2015, at 19:23:49
> > Clonazepam has a half-life of about 18 hours. If you take enough of it twice a day it should be adequate prophylaxis against anxiety and panic all day. You shouldn't have to take it a couple hours prior to stressors. How much are you taking.
> >
> > Alprazolam only works for 4-6 hours and you will have to take it 3-4 times a day to provide coverage. Also, alprazolam does not abort panic attacks...it works fast but not that fast.
> >
> > Eric
>
> I am officially on 20 mg diazepam, but have often added a little under-the-counter clonazepam, most recently to help withdraw from an OTC. I find they make a good combination: It is not well known that diazepam ITSELF has a SHORT half-life (~6 hr), being metabolized mainly into nordiazepam, slightly less effective than diazepam, but with the very long half-life (see Wikipedia for details).
>
> The Clon. seems to help balance out the 6-hour shoulder at which the diazepam SEEMS to stop working.
>
> (As far as panic attacks go, I recommend Ativan sublingual; I've used it in the past successfully, but my pdoc won't prescribe it for me as it more addictive.NOT being able to make GABA? Just use picamilon, it's precursor. I have started using it to try to enhance clonazepam. I need a dose increase in dose. I did ask my pdoc for an increase but no go. Then I had the opportunity to try some gabapentin. My anxiety ruduced a lot.
poster:Escapee
thread:1077818
URL: http://www.dr-bob.org/babble/20150407/msgs/1078899.html