Posted by tom2228 on June 12, 2015, at 21:05:56
In reply to Re: Desipramine Questions, posted by Christ_empowered on June 12, 2015, at 18:45:48
Ok, let's focus on one thing for now -- the desipramine. Most antidepressants have start-up effects that dissipate as the body acclimates to the drug and the therapeutic effects show up. I had a bit of jitteriness/ mild tension/ uncomfortability the first couple days.
Other than that desipramine has been very good to me. In my case Marplan is like the wood that lays the foundation and desipramine lights my fire. My response has been fabulous and it's been one of the more powerful and helpful meds I've
tried. Few sides now except some sweating and dry mouth. I'm on 125mg and I take 75mg at night, 5mg in the morning.I tried nortriptyline which some people prefer and I responded but it had more sides for me and desipramine just works better for my symptoms. Some say nortriptyline is more calming but I find desipramine relaxing albeit it motivating and stimulating. I haven't tried other TCA's but I think it's safe to say that they are different enough, especially compared to the differences between the SSRIs, to warrant giving a fair appraisal to a second TCA. Be patient with yourself and try to make positive life changes and engage yourself in some sort of therapy of you aren't currently. Doing the work, even if it wasn't much at first -- just giving it whatever I could muster -- has made a huge difference and is the fuel that the medications need to work. I wish you strength and patience.
Tom
poster:tom2228
thread:1079697
URL: http://www.dr-bob.org/babble/20150520/msgs/1079722.html