Posted by SLS on July 3, 2015, at 15:26:42
In reply to Parnate 100mg what to do from here?!? Help!, posted by Uncouth on June 13, 2015, at 13:52:13
I agree with everything that was said here about Parnate.
Nardil is better for anhedonia, but often doesn't continue to work (poop-out).
For me, Parnate and the other drugs I take make me more functional because they give me more mental energy and allow me to think a little faster. However, the rest of the depression remains. I don't take this improvement for granted, though.
My longest period of remission (6 months) was achieved with a combination of Parnate and desipramine. It could probably could have lasted indefinitely had the doctor not had me discontinue treatment. You might want to go up to 120 mg/day. This seems to be the minimum that was advocated by Jay Amsterdam and the other "high-dose Parnate" doctors. I am currently taking 100 mg/day. When I go to 120 mg/day, I experience "brain-fog" and some flattening of affect. I certainly lose some functionality. I initially felt better upon the dosage increase, but that improvement was short lived.
Robert_Burton_1621 is accurate in everything he has to say. I wouldn't have thought to write everything that he did.
Currently:
Parnate 100 mg/day
nortriptyline 100 mg/day
Lamictal 300 mg/day
lithium 300 mg/day
Abilify 10 mg/dayIf cariprazine ever comes to market, I would like to substitute it for Abilify. It more potent than Abilify at D3 receptors in limbic structures, and might produce some improvements in anhedonia. I expect theree to be residual depression, though. I am heading in the direction of brain stimulation treatments.
Good luck, Uncouth.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1079745
URL: http://www.dr-bob.org/babble/20150629/msgs/1080187.html