Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: AD for norepinephrine » kribensis

Posted by SLS on July 14, 2015, at 14:35:41

In reply to AD for norepinephrine, posted by kribensis on July 14, 2015, at 13:50:37

> I think that norepinephrine is my issue

How did you come to that conclusion? Just curious.

> and I have trouble finding an AD that works. Any suggestions for ones that act mostly in norepinephrine? (Do not tolerate Wellbutrin). Also needs to be one available in Canada.

The most selective and potent NE reuptake inhibitor is desipramine (Norpramin). Nortriptyline (Pamelor) is predominantly selective for NE also. Both of these drugs are tricyclic anidepressants. Another selective NE reuptake inhibitor is atomoxetine (Strattera). However, it is a better treatment for ADHD / ADD than it is for depression.

An alternative pro-NE strategy is to block NE alpha-2 autoreceptors. Mirtazapine (Remeron) and mianserin (Athymil) both have this property. Of the two, mirtazapine is the least sedating.

Personally, I found venlafaxine (Effexor) 300 mg/day to be more effective with the addition of nortriptyline 75 mg/day. Others do better with the addition of mirtazapine to venlafaxine. Mirtazapine is a better antidepressant at doeages of 45 mg/day or higher.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:SLS thread:1080492
URL: http://www.dr-bob.org/babble/20150629/msgs/1080493.html