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Re: Brintellix - how potent an SSRI and sexual sides? » mikezz

Posted by phidippus on July 15, 2015, at 7:14:20

In reply to Brintellix - how potent an SSRI and sexual sides?, posted by mikezz on July 10, 2015, at 7:57:28

The clinically effective dose range for Brintellix (520 mg/day) spans ~50 to >80% SERT occupancy. SERT and 5-HT3 receptors are primarily occupied at 5 mg, while at 20 mg, all targets are likely occupied at functionally relevant levels.

Minimum therapeutic doses of flouxetine, paroxetine and citalopram produce 80% occupancy for the serotonin (5-HT) transporter (5-HTT).

Brintellix is comparable in efficacy to Prozac, Lexapro and Paxil.

I had no sexual side effects while on Brintellix.

Eric


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