Posted by SLS on July 24, 2015, at 18:58:31
In reply to Lou's response-shdahnownbedur, posted by Lou Pilder on July 24, 2015, at 17:09:39
Strattera = atomoxetine
http://www.ncbi.nlm.nih.gov/pubmed/15554766
"A MEDLINE search was conducted for articles published from 1962 to December 2003 using relevant search terms (psychostimulant, stimulant, amphetamine, dextroamphetamine, pemoline or methylphenidate, atomoxetine, bupropion, monoamine oxidase inhibitor, and selegiline)."
"No documented reports were found in the recent literature of hypertensive crises or fatalities occurring when the stimulant was cautiously added to the MAOI."
I performed my own searches and was unable to find a single case of adverse reaction attributable to the combination of Strattera (atomoxetine) with tranylcypromine. It is understandable that the drug company for Strattera (Lilly) would want to unconditionally contraindicate combinations of its drug with MAOIs. Older medical literature clinged to the notion that one could not combine MAOIs with any other antidepressant or stimulant. In real life, this has since been shown to be erroneous. The most important adverse reactions occur with drugs that potentiate serotonin neurotransmission, such as SSRIs and SNRIs. This includes the tricyclics: imipramine and clomipramine.
Also:
http://www.ncbi.nlm.nih.gov/pubmed/7931221
"These results suggest that reboxetine might be advantageously combined with tranylcypromine, or any MAO inhibitor..."
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1080645
URL: http://www.dr-bob.org/babble/20150629/msgs/1080748.html