Posted by SLS on October 12, 2015, at 21:41:46
In reply to Why doesnt every patient on an MAOI take an NRI?, posted by jaiho on October 11, 2015, at 3:37:28
> NRIs such as Nortriptyline & Reboxetine block the tyramine reaction with MAOIs such as Nardil & Parnate.
> Isn't it logical to add the NRI to an MAOI, to increase its efficiency and safety?Is this a theory or are there scientific studies that demonstrate this? I may have come across some animal studies, but I don't remember.
> I am currently on Nortriptyline 75mg, and looking to add Parnate.
I think most doctors still believe that such combinations are contraindicated. If MAOI monotherapy were to produce a remission in me, I would not want to take any other drugs and experience side effects or worse. Taking a NRI with a MAOI doesn't necessarily confer a reduced risk of the cheese reaction occuring. I suffered a reaction to a few slices of pepperoni while taking a combination of Parnate and desipramine. Once was enough. I currently take Parnate and nortriptyline.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1083371
URL: http://www.dr-bob.org/babble/20150929/msgs/1083399.html