Posted by paulk on November 22, 2015, at 13:10:01
In reply to Re: ketamine-like drugs eg GLYX-13, posted by Lamdage22 on April 6, 2015, at 3:27:11
My take is that depression syndromes may often be inflammatory disease. One of the reasons they use ketamine in surgery is that it reduces inflammation.
If you think of being sick - remove the fever and out ward symptoms - what you have left is indistinguishable to depression. Give interferon (pro inflammation) and you produce depression.
Many of the antidepressants reduce inflammation markers on their own (Nardil, Tricyclics and more ) Could be the effect on catecholamines is just a side effect.
IMO once the medical community realizes this as a paradigm treatment could greatly improve.
My hunch is one can get exposed to some virus and afterwards there is an autoimmune reaction that continues - a post viral syndrome. If you have the wrong genes as well you can end up with life long dysthymia.
poster:paulk
thread:1077977
URL: http://www.dr-bob.org/babble/20151119/msgs/1084128.html