Posted by Christ_empowered on November 28, 2015, at 11:33:23
In reply to Re: latuda and perphenizene, posted by Lamdage22 on November 28, 2015, at 6:00:43
Perphenazine can cause some weight gain...its my understanding that most tranquilizers can, except molindone and ziprasidone. Latuda is more weight neutral than a lot of other atypicals. Sounds to me like he may be over-tranquilized.Metformin, amantidine, alpha lipoic acid, and phentermine have all been studied w/ varying degrees of success in preventing and reversing AP/AAP-induced weight gain. There's that new wellbutrin thing out...Contrave...its naltrexone plus bupropion. Its supposed to help shed pounds w/o any potential for addiction or anything. Wellbutrin can also help people w/ psychotic and mood disorders, as long as the psychosis is well-controlled. I take 400mgs/day in SR form, and I"m slowly shedding some weight.
Why Latuda? Why perphenazine? From what very little I've read on AP+AAP combos (this from a Cochrane Review I skimmed briefly), there can be an increase in risk of TD and other side effects w/o much of a clear benefit, at least at the aggregate level.
Have they ever used anticonvulsants, benzos, antidepressants with him? I'm diagnosed as Bipolar I, but my psychosis didn't really die down until I added 2 anticonvulsants and Wellbutrin. From what I've read, there's often a strong mood component in Schizophrenia, but treatment providers see "Schizophrenia" as the diagnosis and they just keep piling on the antipsychotics.
Hope things work out well for him. Please keep us posted.
poster:Christ_empowered
thread:1084230
URL: http://www.dr-bob.org/babble/20151119/msgs/1084246.html