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Re: Effexor poops out at the higher dosage. » Lamdage22

Posted by SLS on December 2, 2015, at 18:52:42

In reply to Re: Effexor poops out at the higher dosage., posted by Lamdage22 on December 2, 2015, at 10:40:28

> Will do, Scott.
>
> I am not happy to be almost anorgasmic, but i guess its a necessity for me to feel better mentally. I am in quite the distress.
>
> If i feel better mentally, i may not be as dependent anymore on sex to make me feel better.

You are being very logical about all of this. Still, your situation is terrible. I have had a few drugs impair my ability to achieve orgasm. However, Effexor wasn't one of them. I hope this side effect goes away for you with continued treatment. You can always discontinue Effexor if you deem the benefits to be inadequate. However, if it works magic at the cost of sexual side effects, you can then tackle these side effect with drugs like the buspirone you chose. I forget what your experience with Wellbutrin was, but it might reduce sexual side effects and make the Effexor work better. I'm hoping that when you respond to Effexor, the reduction in depressive symptoms will include an improvement in sexual function. The higher the dosage of Effexor, the more that norepinephrine (NE) becomes available as a result of reuptake inhibition. A rush of NE is necessary for orgasm to occur.

There is a drug that might be approved soon for depression and anxiety called gepirone. It has come up for consideration by the FDA several times and has been rejected. Perhaps it will pass this time. It appears to be safe, though. Gepirone is in the same family of drugs as buspirone. It is reported by some to be pro-sexual and has been suggested to be a good remedy for SRI-induced sexual side effects.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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