Posted by SLS on December 30, 2015, at 15:22:46
In reply to Re: low dose abilify as a add-on to move my butt -Oops, posted by Lamdage22 on December 30, 2015, at 12:52:59
> "1 case of liver failure resulting in death or transplant per 250,000 - 300,000 patient-years"
> It is a relative rare occurrence.
As best as I understand it, liver fatality occurs in 1 out of 300,000 people per year OR once every 300,000 years for any one person.
This number is considered to represent a "rare" occurrence according to most references, but knowing the statistic itself allows you to decide for yourself if the risk is worth the benefit. Of course, you can take a very simple blood test regularly to reduce your risk of serious injury. From what I read, if it is going to occur, the appearance of major liver damage will emerge between 6 weeks and 8 months. I am assuming that after taking nefazodone for 8 months, if it doesn't appear, the risk goes down considerably. Some people do demonstrate a modest elevation in liver enzymes, but most do not have to stop taking the drug.
If you were to take nefazadone for the next 100 years, there is a 1 in 3000 chance of developing liver failure. Obviously, even if nefazodone works, you most likely won't have to take it for 100 years. By that time, I think you can count on new treatments to become available, so nefazodone would really be acting as a bridge between now and then.
http://www.wisegeek.org/what-are-patient-years.htm
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1006480
URL: http://www.dr-bob.org/babble/20151225/msgs/1085055.html