Posted by TriedEveryMedication on April 21, 2016, at 12:13:55
Indiana university researchers used brain imaging to see the effect of AC drugs in older adults. The findings look a bit grim.
"Association Between Anticholinergic Medication Use
and Cognition, Brain Metabolism, and Brain Atrophy
in Cognitively Normal Older Adults"http://i2.cdn.turner.com/cnn/2016/images/04/18/risacheretal_jamaneurology_final_inpress_041116.pdf
"Reduced total cortical volume and temporal lobe cortical thickness and greater lateral ventricle and inferior lateral ventricle volumes were seen in the AC+ participants relative to the AC- participants."
"The use of AC medication was associated with increased brain atrophy and dysfunction and clinical decline. Thus, use of AC medication among older adults should likely be discouraged if alternative therapies are available."This would include TCAs, antihistamines, some SSRIs and SNRIs, BP meds.
Partial list of drugs with AC effects:
http://www.agingbraincare.org/uploads/products/ACB_scale_-_legal_size.pdf
poster:TriedEveryMedication
thread:1088356
URL: http://www.dr-bob.org/babble/20160331/msgs/1088356.html