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Re: Brintellix question

Posted by SLS on April 27, 2016, at 7:17:42

In reply to Re: Brintellix question » SLS, posted by g_g_g_unit on April 27, 2016, at 0:51:59

> > > However I have read some good things about Brintellix.
> > >
> > > Have you tried it?

> > I wouldn't hesitate to try it except that I am currently taking Parnate, a MAOI.

> Do you know if any of its target sites might protect against developing akathisia on the drug?

Since Brintellix is not a SSRI nor a dopamine receptor antagonist, I would not expect akathisia to develop. Protective? I don't know. Brintellix is a full agonist at serotonin 5-HT1a receptors. I don't know how this might affect the risk of developing akathisia. However, Brintellix blocks an array of 5-HT receptors, including 5-HT7. This receptor is currently being looked at as a target for antidepressant drugs.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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