Posted by Hello321 on May 12, 2016, at 22:06:19
In reply to Why don't my meds work anymore/make me feel bad?, posted by Axmann on May 12, 2016, at 16:39:32
Over time these meds can make your brain less sensitive to the neurotransmitters they originally increase. Your brain tries to maintain homeostasis, and when it sees the meds doing all the work, your brain is in an even less "healthy" state because of the med. Ive experienced it. Some peoples brains seem to bounce back after these meds screw with them. Some brains just don't.
I think a med called Cyproheptadine worked great to help my brain recover after chronically taking adderall. If you look at the way it works, it's not really clear why it would help at all with this. But if you read into the receptors it blocks off,particularly the 5ht2c receptor, which Cyproheptadine shuts off all activity of that receptor with its inverse Agonism. The 5ht2c receptor in your brain inhibits dopamine release. When it's blocked off, your brain is more free to release dopamine.
I just know when I took adderall for about a month, I felt a lot like you described. Then when i took Cyproheptadine for a few weeks. Slowly increasing the dose as I saw fit, I ended up feeling much better.
poster:Hello321
thread:1088876
URL: http://www.dr-bob.org/babble/20160501/msgs/1088893.html