Posted by Jonhed on October 17, 2016, at 16:35:37
In reply to Researchers eye potential schizophrenia 'switch', posted by PeterMartin on September 19, 2016, at 17:27:06
They have to go another way than with trihexylphenidyl then, cause the anticholinergic medications that was used to treat Alzheimer's before levodopa and dopamine agonists in general, causes psychotic symtoms.
Orphenadrine is one that they mainly used before, so I can very much believe that if the mechanism are reversed, it will be effective against positive symptoms of schizophrenia.
The problem I see in using muscarinic agents are the possible increase of negative symptoms.
I do look forward following the progress though.
Thanks for the link.
poster:Jonhed
thread:1092269
URL: http://www.dr-bob.org/babble/20160928/msgs/1092642.html