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CB1 agonism 5-ht1a autoreceptor desensitization

Posted by linkadge on March 30, 2018, at 18:18:54

https://www.ncbi.nlm.nih.gov/pubmed/22133541

The sustained activation of monoaminergic neurons by cannabinoid drugs can also be related to changes in the function of presynaptic inhibitory α(2)-adrenoceptors or 5-HT(1A) receptors (autoreceptors and heteroreceptors), whose sensitivity is downregulated or upregulated upon chronic CB(1) agonist exposure.


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poster:linkadge thread:1097856
URL: http://www.dr-bob.org/babble/20180212/msgs/1097856.html