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Reboxetine likely coming to US for Nacrolepsy(FDA)

Posted by PeterMartin on October 19, 2018, at 2:17:35

The NRI Reboxetine/Edronax, which has been sold in Europe as an AD for years, looks likely to get approval in the USA as a narcolepsy drug. It's been given Orphan Drug designation and a company is pushing to get it approved. I find it interesting that they don't mention Reboxetine (aka AXS-12) has been sold in many countries for almost 2 decades:

Article: https://www.empr.com/drugs-in-the-pipeline/axs-12-reboxetine-narcolepsy-treatment-orphan-drug-designation-cataplexy/article/808296/

Novel Narcolepsy Treatment Gets Orphan Drug Designation

AXS-12 is a highly selective norepinephrine reuptake inhibitor The Food and Drug Administration (FDA) has granted Orphan Drug designation to AXS-12 (reboxetine; Axsome Therapeutics), an oral medicine in development for the treatment of the symptoms of narcolepsy.

AXS-12 is a highly selective norepinephrine reuptake inhibitor. The Company stated that they plan to begin a Phase 2 trial of AXS-12 before the end of 2018, with results anticipated for the first half of 2019.

"The designation is an important regulatory milestone in the development of AXS-12 for this debilitating condition," said Herriot Tabuteau, MD, CEO of Axsome. "We look forward to starting our planned Phase 2 trial of AXS-12 in patients with narcolepsy this quarter."


Wiki:
https://en.wikipedia.org/wiki/Reboxetine


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poster:PeterMartin thread:1101422
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