Posted by linkadge on April 19, 2019, at 15:11:02
In reply to Anti-Inflammatory Add-On for Depression (Study), posted by PeterMartin on April 19, 2019, at 12:27:56
Yes, I have read studies that suggest both and enhancement and inhibition of antidepressant response.
A few thoughts I have are:
1) It may depend on the anti-inflammatory used. Some of them have additional targets. For example, I believe diclofenac inhibits sodium channels.
2) It may depend on the type of illness. Some depression (perhaps anxious) may be associated with increased inflammation and other types may be associated with immune suppression.
3) It may depend on the genetics of the patient
4) It may depend on the phase of the illness. When an animal, for instance, is subjected to stress, the immune system is activated. Over time, however, the immune system becomes exhausted and there is immune suppression.
Personally, I find anti-inflammatories beneficial, but I use them as needed.
Linkadge
poster:linkadge
thread:1104077
URL: http://www.dr-bob.org/babble/20190206/msgs/1104081.html