Posted by radish on July 5, 2019, at 12:26:30
Hello all. I started Parnate 10mg on Tuesday. By Wednesday I felt a slight improvement and by today, Friday, I feel 20% better with regards to many of the symptoms of my depression:
low mood
amotivation
apathy
anhedonia
hopelessness
irritability/intolerance
disinterest in others
low energy/fatigue
easily frustrated or overwhelmed
paralyzing avoidance of everything
obsessive ruminations
inability to concentrate
debilitating self-loathing and dysphoriaI believe these effects are not all placebo because I typically don't get a placebo effect from drugs, the effects are just so pronounced, and Parnate can start working very quickly as seen before on the forum. I may be in the initial wave of euphoria (although I am not experiencing that level of mood elevation) that I've read comes with the start-up of MAOIs and should not to be conflated with their long-term true anti-depressant effect.
It has NOT begun to affect my two most painful depressive symptoms: various forms of cognitive impairment (except my concentration IS improved!) and severe social anxiety. With regards to my concentration, I am finding it easier to focus at my job, whereas before I would work slowly and be bombarded with intrusive negative thoughts all day. I am able to concentrate on writing this post right now with better focus than I typically have for writing. I hope with time Parnate can improve anxiety/social anxiety because it is the main reason I am seeking psychiatric care. I've heard anecdotal reports from both sides; some people report it increases anxiety, while others state it helps them.
Side effects: It has lowered my appetite. It may be increasing my sex drive/desire. I do crash *hard* 7 hours after taking the dose wherein my mood falters and I generally feel depressed and vegetative again. In a couple weeks I will increase to 10mg twice a day and this should help.
Thanks for reading. I'll post more updates so I can aid my memory and in case anyone is interested.
poster:radish
thread:1105165
URL: http://www.dr-bob.org/babble/20190513/msgs/1105165.html