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Re: What do TRD patients take without an MAIO

Posted by undopaminergic on November 29, 2019, at 11:31:25

In reply to Re: What do TRD patients take without an MAIO, posted by linkadge on November 23, 2019, at 7:58:42

> Selegiline (more selective for MAOB) can be combined with SSRIs (although some doctors may be reluctant to combine).
>
> A worthy trial might be say selegiline + sertraline.
>
> Linkadge

Caution is advised with that combination. I have tried it myself, so yes, it is possible, but it produces serotonin toxicity in a subset of cases.

I might suggest trying TCAs if you haven't. You may combine with a stimulant such as methylphenidate or modafinil if you need a dopaminergic effect.

Cheers,
undopaminergic

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