Posted by undopaminergic on March 26, 2020, at 5:03:42
In reply to Re: Tardive dyskinesia, posted by linkadge on March 25, 2020, at 16:27:38
> I have not. If I recall, you are on clozapine which has a relatively low d2 receptor occupancy. It also has 5-ht1a agonism which is hypothesized to inhibit the development of TD.
>
> LinkadgeI'm actually on 3 anti-psychotics, including clozapine, sulpiride, and cariprazine. Additionally, trimipramine has substantial anti-psychotic activity.
It's crazy, yes, given how diminutive my psychotic symptoms are.
The 5-HT1A agonism was news to me. I also read that it increases dopamine release in the prefrontal cortex in part due to this action.
-undopaminergic
poster:undopaminergic
thread:1109222
URL: http://www.dr-bob.org/babble/20200303/msgs/1109228.html