Posted by linkadge on May 12, 2020, at 15:14:47
In reply to Re: nature article rethinking comorbidity dx's, posted by undopaminergic on May 12, 2020, at 11:41:34
>Yes, and if there *are* neurotransmitter >imbalances, they are likely symptoms and not the >cause.
Exactly. For example, decades of research looking into dysfunctional d2, COMT, DAT, MAO-B etc have yielded little to nothing in schizophrenia research. Some of the genes that have been uncovered are in things like the immune system, cellular adhesion, gene transcription, intracellular stuff (stuff that is way beyond my comprehension).
For bipolar, interestingly, there is some linkage with genes like ANK3 and CACNA1 (which regulate sodium and calcium channels) although potassium channels have been implicated in some bipolar studies (something not affected by conventional mood stabilizers).Linkadge
poster:linkadge
thread:1110060
URL: http://www.dr-bob.org/babble/20200511/msgs/1110084.html