Why GABA works

Posted by linkadge on June 14, 2020, at 15:44:21

Although GABA purportedly does not cross the blood brain barrier (BBB), I have come up with a few explanations for why it works.
1) Gut bacteria can convert GABA into ketones which do cross the BBB and affect mood
2) Immune cells in the blood have gaba receptors which, when activated, systemic inflammation. These inflammatory mediators can pass from the blood to the brain. Hence, reducing systemic inflammation may, in turn, decrease brain inflammation.
Again, these are just theories, but may in part explain why so many people report that GABA does have an effect.
Linkadge

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Why GABA works linkadge 6/14/20
Re: Why GABA works sigismund 6/15/20
Re: Why GABA works » sigismund ed_uk2010 6/15/20
Re: Why GABA works » ed_uk2010 sigismund 6/15/20
Re: Why GABA works rjlockhart37 6/16/20
Re: Why GABA works rjlockhart37 6/16/20
Re: Why GABA works rjlockhart37 6/16/20
Re: Why GABA works linkadge 6/16/20
Re: Why GABA works undopaminergic 6/17/20
Re: Why GABA works Lamdage22 6/17/20
Re: Why GABA works » sigismund ed_uk2010 6/18/20
Re: Why GABA works » ed_uk2010 sigismund 6/18/20
Re: Why GABA works linkadge 6/19/20
Re: Why GABA works undopaminergic 6/20/20
Re: Why GABA works » undopaminergic linkadge 6/21/20
Re: Why GABA works undopaminergic 6/22/20
Re: Why GABA works alchemy 6/22/20
Re: Why GABA works » alchemy linkadge 6/26/20

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