Posted by iforgotmypassword on June 17, 2020, at 8:52:03
In reply to Atomoxetine helping - fingers crossed, posted by linkadge on June 17, 2020, at 7:52:29
I prefer NRIs over methylphenidate (Ritalin) because for some reason they are less likely to uncomfortably drive me and cause movements in my face that I'm prone to to start up--but oddly atomoxetine felt very qualitatively different from desipramine. Desipramine usually had a very under control and voluntary-feeling form of arousal, atomoxetine was less so, and could even be giggly and weird. I could not figure out what could account for this. Wondered for a while if alpha1 adrenoreceptor antagonism of desipramine was important in that calm, in-control feeling. Sadly, I gave up on atomoxetine to get enough of a better impression of it, other than it seemed lacking compared to desipramine--but with some silliness stirring I couldn't place that wasn't abrasive/overstimulated-feeling that desipramine did not have.
poster:iforgotmypassword
thread:1110783
URL: http://www.dr-bob.org/babble/20200511/msgs/1110793.html