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Re: Effexor vs TCA+SSRI? » SLS

Posted by linkadge on October 4, 2020, at 18:45:22

In reply to Re: Effexor vs TCA+SSRI? » linkadge, posted by SLS on October 4, 2020, at 14:23:19

I suppose I could take beta blockers, but there's something about raising peripheral / cardiac norepinephrine then blocking it that leaves me a little uneasy. The highest I went on effexor was 75mg. At this dose I had an almost constant feeling of chest tightness as well as high heart rate and blood pressure. This resolved within 24 hours of switching to sertraline. I don't quite understand effexor. I didn't get this on nortriptyline 75mg (which should have had a much more potent effect on the norepinephrine transporter). I am in the camp that says there are yet undiscovered properties of effexor which lead to BP elevations at relatively low norepinephrine transporter inhibition.


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