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Re: Mirtazapine worked really well for anxiety, but

Posted by linkadge on March 24, 2021, at 15:42:54

In reply to Re: Mirtazapine worked really well for anxiety, but, posted by TriedEveryMedication on March 24, 2021, at 10:45:50

Mirtazapine does not have a significant affinity for 5-ht1a.

See:

https://en.wikipedia.org/wiki/Mirtazapine

Keep in mind that larger numbers represent a LOWER affinity of the drug for that target. Mirtazapine exerts its strongest effect at the histamine 1 receptor. Hence you will notice that for the histamine receptor, the number is the smallest:

H10.141.6 (highest affinity)
5-HT1A3,3305,010 (quite low affinity)

Linkadge


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