Posted by jay2112 on July 24, 2021, at 15:31:23
Hi everyone:
Well, I am on a combo of Effexor, Remeron, and nortriptyline. Have been for over a month.
Now, I am, I guess, 'mild' asymptomatic, with a major reduction in my cPTSD (complex PTSD) symptoms, in particular a reduction in consistent crying, and extreme vegetative symptoms. As well as startle effect, and freezing behaviour.
But, I DID, when started notrip, go out for regular tasks (reduced agoraphobia) and felt less pain (I am anemic, and can't take iron suppliments because of kidney disease.) But now, a month later, I am having increased pain, apathetic symptoms (like on an SRI), anhedonia has returned, and increased diarrhea (despite notrip's anticholinergic properties..also like an SRI symptom). I have to mention, these effects are above and beyond my original Rx of Effexor and Remeron, which I have been on, in a combo, for over 5 years. (Sorry, I forgot to mention that I am also on Vyvanse, for over 11 years.)
The notriptyline isn't even giving me the bottom end boost it did when I was on fluoxetine for over 10 years. That is what I am looking for, that 'anti-lethargic' feeling I got from nortriptyline. It gave me the boost sort-of like (but smoother) that I got from Vyvanse.
Take-away: should I boost the nortriptyline (which I did, recently, with only major caffeine-like jitters, which I *absolutely HATE*.) or add some other kind of norepinephrine/dopamine boosters?
One of the problems,which I hate, and think contributes to tolerance and failure of many drugs, is downregulation of the receptors.Should I possibly try a small amount of l-tyrosine, or l-phenylalanine, (d-phenylalanine didn't make any difference in the past.)? I am honestly looking for complementary alternatives, as I have tried about 98 percent of psychiatric Rx's available in Canada. *Note...I have also tried increasing all of these doses, as well as dropping one med at a time for a minimum of 4-6 weeks, with mostly nasty side-effects.
Thanks,
JayHumans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-
poster:jay2112
thread:1116085
URL: http://www.dr-bob.org/babble/20210723/msgs/1116085.html