Posted by undopaminergic on September 20, 2021, at 8:20:30
In reply to Re: ritanserin, pimavanserin, and lumateperone » undopaminergic, posted by linkadge on September 19, 2021, at 16:10:43
> >venlafaxine does not attenuate the tyramine >pressor effect.
>
> I've heard that the in-vivo inhibition (by effexor) of the norepinephrine transporter is higher than would be indicated by traditional measures ...
>I've heard that too. But it sounds to me like it may be marketing.
> and may point to an alternative binding site for effexor towards the norepinephrine transporter.
>If it inhibits the noradrenaline transporter through some alternative binding site, wouldn't it inhibit the tyramine pressor effect?
> I had hypertension on effexor at 75mg.
>Could it be, for example, an imidazoline receptor antagonist?
https://en.wikipedia.org/wiki/Imidazoline_receptor
Or could it be a metabolite?
-undopaminergic
poster:undopaminergic
thread:1116890
URL: http://www.dr-bob.org/babble/20210723/msgs/1117009.html