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Re: Parnate and fatigue

Posted by undopaminergic on March 5, 2022, at 10:00:21

In reply to Parnate and fatigue, posted by Ben on March 2, 2022, at 7:39:35

> Hello

Hello!

> I have bipolar disorder type II
> I am taking Parnate since several years along with other meds (see below). The mood is quite stable but I experience most days a bad fatigue in the afternoon. I tried to split the Parnate dose but if I take the second dose too late I have problems with sleep. If I forget to take the second one I also have the fatigue. Beside the fatigue I have anhedonia and a lot of weight gain. I am thinking its time to change the medication. When I remember right, I was reeding from Scott, that the TCA Nortriptylin is better than Doxepin in this case of problems?! Do you have any ideas or experiences ?
>

Two thoughts:

1) Try to get off the doxepin, it is very sedating; even if you take it at night, there may be a "hangover" next day. If you need its antidepressant effects, then yes, nortriptyline could be a better alternative.

2) Maybe introduce a stimulant; be cautious, especially with amphetamines, but even methylphenidate can be problematic in certain sensitive individuals.

-undopaminergic


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poster:undopaminergic thread:1118824
URL: http://www.dr-bob.org/babble/20220128/msgs/1118867.html