Posted by SLS on August 4, 2022, at 20:02:12
In reply to Re: Retrying escitalopram, posted by linkadge on August 4, 2022, at 17:25:04
Hi, Linkadge.
How much lithium have you been taking?
I'll write more about Alzheimers later. I wanted you to see this, though.
"Forty seven severely depressed patients who failed to respond to 300-375 mg/day venlafaxine were, in addition, given lithium carbonate in low dosage (300-450 mg/day). The Clinical Global Impression Improvement scale was used as the treatment outcome. A score of 1 or 2 was considered as non-response. All patients gave informed consent to participate in the study. Ratings were performed at baseline and after 1,2 and 5 weeks. Lithium plasma concentration measurements were performed after 1 and 4 weeks. After 5 weeks of augmentation, 51% of the patients were rated as "much" or "very much" improved. Bipolar patients showed a better response than unipolar (64.3% vs 45.5%, p<0.038). Most patients (76%) showed a rapid response (up tp 7 days), and only 2 patients (4.6%) responded after more than 2 weeks The mean lithium plasma level was 0.33±0.09 mEq/L. "
https://pubmed.ncbi.nlm.nih.gov/22796912/
Also, regarding the bimodal effect of lithium on glutamate concentrations:Low Li+ = High GLU
High Li+ = Low GLUhttps://pubmed.ncbi.nlm.nih.gov/25522399/
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1120203
URL: http://www.dr-bob.org/babble/20220530/msgs/1120214.html