Posted by tealady on September 17, 2003, at 6:38:27
In reply to Re: Something to lose weight » tealady, posted by Kacy on September 15, 2003, at 14:43:29
> Thanks, again, for the knowledge. For once, I'm covered. I take it with a folic acid mix that has 25 mg B-6 Pyridoxine HCI–that's 1,250% of the rda–and with a zinc supplement that has 20 mg of the same B6–another 1000% of the rda.
sounds good..most folks don't need any more B6 than that. On a daily basis most women need 20mg to 50mg. Any more than 25mg used to give me migraines...but there again some folks can take 100mg
> I see nothing on those, however, that says P5P. I am over forty.Well I can't get P5P in Oz, I have one precious bottle from the US..I really do need more but it is exxy to bring in. Another "illegal" in Oz.
And I've been ringing around and can't get NADH either. still to ask a few alternative docs if perhaps they bring it into the country! Tried all chemit I can think of.
But the story is pyridoxal 5 phosphate(P5P form of B6) is the biologically active co factor ( post liver metabolized B6)..what you get after your liver has digested the B6 properly.
A large percentage of women over 40 don't have the stomach acid or something that allows one to properly absorb B6 and in general women lose the ability more as they age.
Taking an enteric coated form of p5P B6 separately by itself (as it is enteric coated..like you can't cut the tablet) allows the stomach and liver to be bypassed and hopefully one absorbs in the intestine! We only need about 20mg of this P5P form..unless there is a problem to correct when we may need 20mg P5P twice a day.
This form is used to with tyrosine hydroxylase ..something to do with adrenals. '
Wait I'll look for a link
"B6 or pyridoxine is essential for the metabolism of protein as it helps to convert glycogen into glucose which can be used by your muscles for energy. It's an important co-factor in the regulation of 26 aminotransferases, enzymes that regulate the proper pathways for our neuroendocrine system. If you are deficient in B6, you may form kidney stones when you eat sugars such as fructose or galactose. Women need higher doses of B6 than men because we lose more B6 in our urine. Women taking birth control pills to control menopausal excess bleeding can become depleted of B6, which results in disturbances in the metabolism of tryptophan. This can cause depression, anxiety, decreased sex drive and impaired glucose tolerance. B6 is important in lowering homocysteine levels in blood. Pyridoxal-5-phosphate, the liver metabolized form of B6, is the active component. However, if you have problems with gastric emptying, you may not be able to absorb B6 from standard vitamins unless it has been treated for absorption in the small intestine or duodenum."..from http://www.menopausediet.com/Store/products.htm
but you can buy it other places...if you do, make sure it is enteric coated as it has to bypass your liverB6 is the starting element. The ideal is a NORMAL STOMACH..which most of us women with problems don't have....and then liver enzymes break B6 into P5P, the ACTIVE form of B6. I've read women lose twice as much P5P as men but we don't make as much as men. So we tend to be a bit short.B
B6 is cheaper and better than taking nothing at all.
And too much B6 does lead to migraine s and can be toxic.
Some folks take a combo of P5P and straight B6...I guess to reduce cost and "cover" themselves?
> Did I see some post of yours recently about zinc in the picolinate form that was a bad form to take? After I finished my zinc/B6 mix, I was going to finish up a bottle of zinc as "zinc citrate, histidinate, picolinate, alpha-ketoglutarate, aspartate". Is there something wrong with that?
>Yes I was asking Lar about the picolinate form..see
http://www.dr-bob.org/babble/alter/20030903/msgs/257782.html
or in that threadI tried some zinc picolinate and it did seem to give me a much stronger zinc effect..so I'm not too sure on the chelation, and lots of folks swear by it..but I would definitely myself NOT take it routinely..only occasionally, and I don't think I'll buy another bottle when this one runs out.
I really don't know enough to comment , but I would guess it would be OK as you are only getting a little bit as it is in lots of forms..how much of each are you getting? Perhaps when it runs out you could look around for a different type? The B6 with zinc is good..if you do end up with too much B6 and get headaches, you know what to suspect.Jan
poster:tealady
thread:258507
URL: http://www.dr-bob.org/babble/alter/20030903/msgs/260920.html