Posted by Larry Hoover on November 26, 2004, at 13:52:35
In reply to Re: magnesium, posted by linkadge on November 26, 2004, at 13:14:56
> I find if I take more than 250mg of magnesium in supplement form, I start to feel "really incapable". Kind of like what I was like on therapudic dose of lithium.
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> I am on 600mg of lithium and I don't know if taking magnesium with this would be safe?
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> The first time I combined magnesium with lithium I got really strange body jerking.
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> Doesn't lithium raise blood levels of magnesium or something ??
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> LinkadgeLithium ions act on the parathyroid gland similarly to low calcium levels. Perhaps lithium ions block the calcium receptors, and hinder the response of the parathyroid? In any case, the increased parathyroid hormone causes demineralization of bone, and with it, increases in serum calcium and magnesium. The kidneys would ordinarily retain both magnesium and calcium under this condition (high PTH), but the increased diuresis caused by lithium causes net loss of magnesium.
Rat studies showed lithium-induced loss of magnesium from soft tissues, so it could be that humans do that too.
Maybe you'd do better if you split your magnesium dose, or took it only at night?
Lar
poster:Larry Hoover
thread:419531
URL: http://www.dr-bob.org/babble/alter/20041123/msgs/420541.html