Posted by Dan Perkins on December 18, 2004, at 20:40:27
In reply to Re: MAOI + Tryptophan » Dan Perkins, posted by Larry Hoover on December 18, 2004, at 10:03:51
So, the idea seems to be that MAOI + Tryptophan is a no no for the same reasons that MAOI + SSRIs is a no no. In my mind, this is a good indication that Tryptophan really is powerful enough to effect serotonin levels and that it may just be a good thing for me.
> I would say that the risk is proportional to the dose. It may be an excellent combination, but it ought to be a well thought out one.
>
> The biggest undeterminable variable is your own biochemical response. The difference could be tenfold or more, in different people.
>
> You get tryptophan every day, in your diet. Your brain requires some tryptophan every day. There already is an interaction between the MAOI and tryptophan, but the magnitude of the interactions cannot be known accurately. If you want to tweak tryptophan, you need to be able to do it with precise control. I'd say dose control at the 100 mg level would be necessary.
> And, it would be a good idea that you recognize the symptoms of serotonin syndrome. Here's one resource: http://www.anxiety-and-depression-solutions.com/serotonin-syndrome.htm
>
> Lar
>
poster:Dan Perkins
thread:430933
URL: http://www.dr-bob.org/babble/alter/20041212/msgs/431430.html