Posted by Tooooja on February 16, 2005, at 5:21:36
In reply to Re: Biounavailable Copper » Tooooja, posted by Larry Hoover on February 14, 2005, at 19:06:38
Hi,
I've done a search on pubmed to see if there's anythong on ceruloplasmin adrenal interaction and it's turned up these results, see what u think:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6251525
"Response of caeruloplasmin to Escherichia coli endotoxins and adrenal hormones in the domestic fowl.
Curtis MJ, Butler EJ.
The injection of chickens with Escherichia coli endotoxins immediately produced a 50 per cent rise in plasma caeruloplasmin activity which was attributed to the release of the protein from liver cell. This was followed by a fall in activity, which was probably due to a fall in activity, which was probably due to a stabilising effect of adrenocortical hormones on the cell membranes, and then by a five-fold increase. The results of experiments with cycloheximide, adrenocorticotrophin, beta-methasone and reserpine indicated that the third phase of the response reflected increased synthesis in the liver which was partly induced by adrenal hormones. It increased with the dose and was not elicited by the particulate nature of the toxin preparation or by its lipid and polysaccharide components."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7325187
"Influence of synthetic corticosteroids on plasma zinc and copper levels in humans.
Yunice AA, Czerwinski AW, Lindeman RD.
The effects of varying doses of a short-acting (methylprednisolone) and a long-acting (dexamethasone) synthetic glucocorticoid on extent and duration of alterations in plasma zinc and copper concentrations in normal humans are documented. Early after intravenous administration of either steroid, increases in plasma zinc and copper levels were observed. By 12 hours, plasma zinc concentrations had decreased below control levels and the extent and duration of the depression depended on the dosage of the steroid administered. No significant decrease was noted beyond 48 hours. The plasma copper levels did not decrease until after zinc levels began returning toward normal, reaching a peak depression at 48 hours and, at high doses of steroids, persisting until completion of the study at 96 hours. This difference in the time sequence suggests that different mechanism control plasma concentrations of the two metals. The serum zinc levels may depend on ACTH-adrenal interactions, while the slower response of the serum copper levels may depend on changes in the rate of synthesis of the serum copper-binding protein, ceruloplasmin."
No abstracts for these other ones unfortunately.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=5417413
"Regulation of hepatic copper in the rat by the adrenal gland.
Gregoriadis G, Sourkes TL."
poster:Tooooja
thread:457586
URL: http://www.dr-bob.org/babble/alter/20050131/msgs/458642.html