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Does MAO-B activity vary from person to person

Posted by linkadge on April 25, 2005, at 14:39:47

In reply to Re: does b12 effect MAO-B ?? » linkadge, posted by Larry Hoover on April 25, 2005, at 8:52:58

I mean I have often asked myself this and similar questions, but really there doesn't seem to be an answer.

If MAOI's work for depression, does that mean that MAO activity is higher in some people with depression.

Its just like the idea of reuptake. Is the reputake of serotonin actually higher in depressed people. If so, why don't undepressed people have sexual problems, apathy, insomnia, and other SSRI related side effects.

Sometimes I just don't buy the whole serotonin gene thing. Especially since the rats that these drugs are tested on are likely to have normal serotonin uptake.

Does serotonin uptake vary from time to time in the same individual ?? Does stress actually change the uptake of serotonin.


Ask you can see, I am having a real crisis of belief. I bought the whole serotonin gene thing a while back, but when the drugs pooped out I lost that feeling of empowerment. That feeling like I could pinpoint the source of my problems. That feeling like I could prevent ever going there again. How utterly wrong I was.

I am starting to believe the more depressing outlook/possability that depression is just a natural and enevitable responce to the unavoidable stress in our every day lives.

Did you know that after one war in Serbia, one study found that 85% of people met the criteria for major depression.

Everone wants to believe that they have found the secret to happiness. I think this is just a time limiting, self serving bias. It is just like the placebo effect. Something that we can blame our suffering on, other than reality.

I mean *everbody* is on an antidepressant these days. I mean that almost literally "everbody".
It really tweeks me too, cause when everbody has an illness then nobody has an illness.


Sorry, this post has little to do with the title :)


Linkadge


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