Posted by JLx on May 8, 2005, at 11:53:42
In reply to Re: Melatonin:reduce toxicity incr efficacy of drugs, posted by Declan on May 8, 2005, at 1:19:11
> There is a precaution for its use with people who are depressed; you can perhaps find it in the faqs section on this board. Don't think it's made me any more depressed. Doesn't help my sleep either.
> DeclanI've tried it and yes, it can increase depression. I believe it may be dose dependent. I've seen recommendations for much higher doses than I've found advisable.
I've used it successfully for sleeping, in tiny doses -- a quarter of a 3 mg tablet.
I think it's important to take it early enough at night too. Iow, not just before one wants to try to fall asleep but an hour or perhaps even 2 before.
The trouble comes in next day feeling down.
Looks like the comments on this page confirm my experience:
"Depression: 0.125 mg twice in the late afternoon, each dose four hours apart (for example, 4 PM and 8 PM). People with depression tend to be particularly sensitive to the effects of melatonin -- meaning that a very low dose is generally enough to get the desired outcomes."
http://www.umm.edu/altmed/ConsSupplements/Melatonincs.html
JL
poster:JLx
thread:494971
URL: http://www.dr-bob.org/babble/alter/20050414/msgs/495186.html