Posted by Declan on August 19, 2005, at 1:26:01
In reply to SAM-E with an MAOI?, posted by EERRIICC on August 16, 2005, at 23:55:56
Hi Eric
I'd taken 400mg/d SAMe for years and when I started Parnate 10mg/d got an immediate and positive response, which developed into an agitated feeling that went away when I discontinued the SAMe. I'm fairly sure it was seratonin related because...
1. I'd found discontinuing SAMe difficult in the past due to a cold bleak feeling, which was no problem with Parnate 10mg/d in place.
2. I've never had that agitated feeling on deprenyl, bromocriptine, cabergoline, amphetamine.
3. Agitation eventually returned when I added the plant based seratonin analogue, Seroctin, to the Parnate.
Anyway I think the combo stimulated one of the seratonin receptor subtypes responsible for agitation. It wasn't the same anxiety as I'm used to it. I felt a bit freaked out. Since you take a fair bit of Parnate I'd be cautious with the combination.
Was the amineptine/Parnate combo OK?
I've taken different chinese herbs for depression, in herbal formulas made for me. Nothing magic, that's why I'm trying a bit of Parnate. Still, it's all very interesting.
Declan
poster:Declan
thread:542774
URL: http://www.dr-bob.org/babble/alter/20050812/msgs/543769.html