Re: Does 5-htp bypass tryptophan hydroxylase ? » linkadge

Posted by Larry Hoover on October 30, 2005, at 7:28:07

In reply to Does 5-htp bypass tryptophan hydroxylase ?, posted by linkadge on October 29, 2005, at 16:15:59

> I've been reading a number of studies on depression possably being linked to bad a tryptophan hydroxylase gene.
>
> Can somebody explain to me what is bypassed by taking 5-htp over tryptophan? Is tryptohpan hydroxylase needed after 5-htp ?
>
> Linkadge
5-HTP is the product of tryptophan hydroxylase. Ergo, if one is deficient in that enzyme, 5-HTP is the stuff to take.
The only problem is, the next step is much less specific and unique. 5-HTP is converted to serotonin by decarboxylase, and those enzymes are ubiquitous.
The way the healthy body ensures that serotonin is only produced where it is needed is by localizing tryptophan hydroxylase. Oral 5-HTP tends to promote serotonin formation wherever the blood happens to take it.
Lar

Thread

Does 5-htp bypass tryptophan hydroxylase ? linkadge 10/29/05
Re: Does 5-htp bypass tryptophan hydroxylase ? » linkadge Larry Hoover 10/30/05
Re: Does 5-htp bypass tryptophan hydroxylase ? linkadge 10/30/05
Re: Does 5-htp bypass tryptophan hydroxylase ? teejay 10/30/05
Re: Does 5-htp bypass tryptophan hydroxylase ? » linkadge Larry Hoover 12/4/05

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