Posted by jparsell82 on April 24, 2006, at 9:30:53 [reposted on April 24, 2006, at 19:03:29 | original URL]
In reply to Natural or medicinal 5ht2 antagonist?, posted by blueberry on April 22, 2006, at 5:53:58
Chromium shows promise in atypical depression.
Biol Psychiatry. 2003 Feb 1;53(3):261-4.
Effectiveness of chromium in atypical depression: a placebo-controlled trial.Davidson JR, Abraham K, Connor KM, McLeod MN.
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA.
BACKGROUND: Chromium picolinate (CP) has been reported to benefit patients with symptoms of atypical depression. METHODS: A placebo-controlled, double-blind, pilot study of CP was conducted in 15 patients with DSM-IV major depressive disorder, atypical type. Patients received 600 micro g of CP or matching placebo (PBO) for 8 weeks. RESULTS: Seven (70%) CP and zero (0%) PBO patients met responder criteria (p =.02). Other outcomes were consistent with greater effect of CP. Three patients on CP failed to show any improvement. Chromium picolinate was well tolerated. CONCLUSIONS: Chromium picolinate shows promising antidepressant effects in atypical depression. Its mechanism of action may relate to 5HT2A downregulation, increased insulin sensitivity, or to other effects.
poster:jparsell82
thread:636663
URL: http://www.dr-bob.org/babble/alter/20060313/msgs/636667.html