Posted by Tomatheus on November 9, 2006, at 18:25:29
In reply to magnesium insomnia, posted by qqqsimmons on November 6, 2006, at 18:25:45
> maybe it's like how beta blockers suppress adrenaline and inadvertedly wind up messing up folks melatonin...so that even though they're tired all the time, they can't fricking sleep at night.
>
> is our melatonin release at night dependent on a certain amount of adrenal action during the day?Actually, I remember reading a medical journal article stating that stimulation of the beta receptor is a necessary step in the synthesis of melatonin. I don't have the article with me right now, but if you need a citation, let me know, and I'll get you the info.
I personally suspect that the beta receptor's role in the production of melatonin could be part of the reason why meds that inhibit the reuptake of norepinephrine seem to have a paradoxical depressant effect (or at least an inconsistent antidepressant) effect in some individuals. That's basically just a wild theory of mine, though, not any kind of authoritative knowledge.
Tomatheus
poster:Tomatheus
thread:701035
URL: http://www.dr-bob.org/babble/alter/20061013/msgs/702124.html