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Re: Is there a connection - SAM-e -- Glutathione?? » Jimmyboy

Posted by tealady on November 24, 2006, at 19:48:42

In reply to Re: Is there a connection - SAM-e -- Glutathione??, posted by Jimmyboy on November 24, 2006, at 12:52:30

I agree with your doc too.
I was low on glutathione a over a couple of years ago and got my levels up.. mainly by food. My body now eats high glut foods when it wants em:)
I also responded really well to SAMe.. although I only ever tried one packet of them.. I tapered off during taking the packet. My packet was SAMe joint formula and I've mentioned it before on here somewhere I think.. the fastest lift out of depression I have had.
I did notice it a little after I ran out, even with tapering though.. but I was better than before i took the SAMe.
Quercetin (I think) works best too when Glutathione levels are normal.
I'll try to find some old gluathione posts.
It was somethimng that really helped ..I remember that much.
I did try some whey (a coiuple of jars ) at the time too to get glutathione levels up.. yes it works too..as I think does watermelon and strawberries(which I ate a lot of), and a few other foods I'll have to try to recall.
I know once my levels were up and I was feeling a lot better , but not perfect then I no longer craved the glutathione high foods.

I found these old links which may help
http://forums.about.com/n/pfx/forum.aspx?msg=3428.6&nav=messages&webtag=ab-thyroiduk

then I wrote this somewhere around that time too
++++then

http://www.vrp.com/art/1783.asp?thenews=vn00a000b01005-1783

here's where it fits in with more vulnerable to damage by nitric oxide or peroxynitrite as well as the heart stuff

study authors, “These findings suggest that reduced plasma total glutathione levels are a risk factor for CVD, especially for cerebral small vessel disease.”

Australian researchers established a similar link between glutathione and cardiovascular health.4 When the researchers caused a drop in glutathione levels in the mitochondria of cultured brain cells, the cells became more vulnerable to damage by nitric oxide or peroxynitrite.
--------------------------------

now for the glutiathione stuff read this thread.

The link is
. Mercury interferes with sulfur bearing compounds throughout the body, and can interfere with the ability of the body to synthesize Glutathione.

http://www.dr-bob.org/babble/alter/20040928/msgs/401517.html
http://www.dr-bob.org/babble/alter/20040928/msgs/400940.html
http://www.dr-bob.org/babble/alter/20041108/msgs/415903.html
http://www.dr-bob.org/babble/alter/20041022/msgs/411464.html

well read the whole thread around there...

it's where I formed ideas as to the antioxidant mix. before then I'd had a lot of trouble.. like too much CoQ10 actuially increased oxidation after a while.. bt that was with fish oil ..and the alpha only VitE form. Now I take the mixed tocopherols and a balance is needed...

Yes, it is all related to mitochondria.. and probably iron-sulfur.. remeber my dificulties getting ferritin up?

Lactoferrin helps :-)

Love and best wishes,

Jan
-------------------
and I wrote this

http://forums.about.com/n/pfx/forum.aspx?msg=3428.8&nav=messages&webtag=ab-thyroiduk

**
http://www.cfsn.com/detox.html
http://www.cfsn.com/secure.html#anchor5482706

interesting stuff...seems to fit me too...on vitamin C and glutathione* especially after the previous reaction with an amalgam removal... craved glutathione foods when in England last year and for months around then.. getting better this year
but then I needed ......VitC..and a lot of it too!
Just reached tolerance in last couple of days(after an amalgam removal done without any precautions..typical! any Aussies know any good dentists??) , and also after shingles.. just recovering from, and a previous episode of coughing up some blood..and small lumps of tissue felt like from throat(orange pith helped!!.. thanks Bob : ).. backing off slowly.. but looks like I may need a minimal level of say 1/8 teaspoon.. 500mg twice a day?

http://www.cfsn.com/histidine.html
"L-histidine is essential in forming many metal bearing enzymes and compounds, examples being the antioxidant super oxide dismutase, the iron storage protein ferritin, the iron uptake regulation protein -FUR, the copper storage and iron metabolism cofactor cerulplasmin, red blood cell hemoglobin, the toxic metal storage protein metallothionein, and the cysteine regulating enzyme cysteine dioxygenase - to name but a few important enzymes dependent on L-histidine being available for formation and function."

(I can't remember if I mentioned this or not, ) You can see where ferritin comes in...

and Larrian was talking about this histamine/histidine somewhere to me too...
Jan
---------------------

and also this

http://forums.about.com/n/pfx/forum.aspx?msg=3428.9&nav=messages&webtag=ab-thyroiduk

Bad luck about reality and expectations not meeting re the hospital. Did they test anything? Sent you some emails.

What I've had great improvement with is orange piths(that's the white bit under the skin), especially not the navel ones but the more bitter kind are helpful. Marmalade jam is probably helpful in this way too .

also glutathione foods.. like strawberries, watermelon (I love the juice).. wheatgerm should fit in here too (if you aren't on a gluten free thing), avocodao (I just use a litle instead of butter.. unless its with amarmalade jam Of course!Tastes great with say a staek sandwich or a hamburger though)

List of foods frm somewhere.. I'm unable to find a list of specified meaured typical food glutathione content.. I don't thik it's beeed done as yet!

Here's some they have found glutathione in though

asparagus, watermelon (excellent source), potato, strawberries, oranges,tomato, broccoli, peaches ... all of these I love, except asparagus.. which I have to try when I remebmer what to do to make them taste good?

grapefruit, (wary of as it inhibits that liver enymze so don't over do it).. bitter oranges are supposed to do the same. It may the method of increasing glutathione.. by slowing down liver to allow more glutathione left for other stuff? .. or maybe they increase glutathione in another manner as well ?

zucchini, and spinach (be wary of too much spinach re nitrates.. I've done that one..documented on thyroid forum)

acorn squash,acorn squash, okra, .. well they must be US foods as I've never heardof em

Now do you want any more ideas, or do you already think I'm mad enough:-)
------------------

I think the white pith of a more bitter orange contains quercetin? ..or at least its high in flavanoids (of which quercetin is one)..and it works better if glutathione levels are up.. so best if take both together :)
--------------

not sure if this helps at all, hope its not too dispointed, but glutathione foods and the orange piths seemed to help me
I don't seem to have time to loo at this again at present, but I continue to eat starbwerries, and oranges including the piths . My oranges aren't the sweet californian ones(APPARENTLY THEY DONT WORK SO WELL)..they are the more bitter valencia? I think? ones

I you feel , "gee I'm sick of XXX",then your levels are up to normal and you can back off...


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poster:tealady thread:706531
URL: http://www.dr-bob.org/babble/alter/20061118/msgs/706848.html