Posted by willyee on November 30, 2006, at 9:39:06
In reply to Accidentally disovered something, posted by aeon on November 29, 2006, at 18:22:46
> Hi again
>
> News from the laboratory of my mind.
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> I have been really interested lately in the NMDA glutamate theory of neurotoxicity in depression and other disorders.
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> I am terribly sensitive to free glutamate (eg:in msg, soya sauce, yeast extracts etc) so I decided to see if I could help my brain.
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> Using the theory of glutathione being a good antioxidant I took 1 gram of cysteine planning to take that much each day and add lipoic acid too.
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> Didn't get that far because the cysteine caused a massive worsening of symptoms... first irritability then extreme anxiety, to panic, to a full blown curl up in fetal on the couch depression.
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> Once this reaction passed a little I felt headachy and tired and dysthymic I thought wow that sucked but started to try to understand why.
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> Turns out Cysteine is a neurotoxin, and is an NMDA agonist, which means it increasese NMDA caused neurotoxicity. The reaction I had was similar to when I consume msg.
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> Anyway I started researching for NMDA antagonists... guess what? Magnesium is a great antagonist of NMDA. Also carnitine as it turns out.
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> So I took 500mg acetyl-l-carntine and 800mg mag orotate.
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> The effects were rapid. It reversed all the cysteine induced problems and gave me a great sensation of energised relaxation in its place. An absolutely wonderful amelioration.
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> This morning I have repeated the concoction and the same response is evident.
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> I am wondering now if my problems are NMDA/glutamate related at their source...
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> Is it possible that the acetly l carnitine is delivering magnesium to the brain, maybe the body forms magnesium carnitate? then they work some kind of NMDA antagonist magic?
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> I have never experienced benefit from magnesium before though have tried it multiple times in different forms, and carnitine I usually notice no real effects from, its just supporting nutrient.
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> Together though they seem to have a wonderful synergistic effect.
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>Dident you just strongly recomend a HIGHLY expensive combo to the group already,if it was working so well,why would you continue to be trying stuff,no insult here,just i was one who bought ur recomendation and i have over 20 bucks of supplements sitting on my desk,totaly waste for me.
poster:willyee
thread:708717
URL: http://www.dr-bob.org/babble/alter/20061118/msgs/708950.html