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Re: Why would folic acid help depression? » Jimmyboy

Posted by dessbee on January 5, 2007, at 11:53:41

In reply to Why would folic acid help depression?, posted by Jimmyboy on December 30, 2006, at 14:35:03

Folate is needed to replicate DNA/RNA and may improve neurogenesis.
Folate deficiency will affect cell division, especially cells with rapid cycles like formation of red blood cells.

Folate is used in the Methionine Metabolic Pathway to regenerate methionine from homocysteine, which is a risk factor for depression.
Folate may increase S-adenosylmethionine (SAMe) through the replenishment of methionine.
S-adenosylmethionine (SAMe) is used in the synthesis of epinephrine.

Folate is not directly involved in synthesis of serotonin/dopamine/epinephrine

Folate can increase histamine levels, which may aggrevate sleep quality and increase inflammatory processes.


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poster:dessbee thread:717599
URL: http://www.dr-bob.org/babble/alter/20061218/msgs/719587.html