Posted by tonyz on May 1, 2009, at 11:42:04
I am wondering about those that have some experience taking SAM-e. How many years have you taken it and at what dosages? One of the potential complications with SAM-e is the increase in homosysteine levels. The homosysteine can be reduced by taking additional supplements which can reduce the need for taking larger amounts of SAM-e. This is stuff I read on the web about the methylation process. It makes sense, but I am looking for some supporting evidence. One article I read recommended supplementing SAM-e with 100 mg B6, 1mg B12, 500-2000 mg trimethylglycine and 1mg folic acid. From what I understand the B vitamins are water soluble so if you take too much your body will just eliminate them naturally; however, I don't know much about trimethylgycine and folic acid so I don't know of any complications with these levels?
Co-Q10 is also supposed to reduce homosysteine levels so I am wondering if that would be a good supplement as well.
The most effective antidepressants for me have been Nortrityline and SAM-e (NOT AT THE SAME TIME)
Taking tricyclics and SAM-e together can be very dangerouse because of the risk of serotonin shock.Everyone's mind and body reacts differently, it is unfortunate that there are no clinical tests that can determine what is the precise drug for each person.
I can't speak for others as to their symptoms and problems and how they choose to treat their illness, but for me I would prefer to avoid the pharmaceutical route if at all possible. The doc I am seeing now is supportive of this approach and I would encourage anyone to discuss with their doc before making any changes.
Lastly, I'm not sure if this is the right place to be posting this. I will also post on the alternative board.
Current meds/supplements taken now
diazepam 10mg
SAM-e 400mg
vitamin e 200mg
Daily vitamin
co-q10 100mg
Calcium 500mg
Vitamin C 500mgThanks in advance for any feedback.
poster:tonyz
thread:893721
URL: http://www.dr-bob.org/babble/alter/20090410/msgs/893721.html