Posted by nolvas on January 14, 2010, at 5:33:04
In reply to sale on but what the hell is safe, posted by manic666 on December 30, 2009, at 13:04:45
You can combine Korean Ginseng, Green Lipped Mussel and Zoloft together. You however should not combine Valerian with Sertraline. See the searches I have done below for you. (I have an account at the site).
Natural Medicine Comprehensive Database :Zoloft (ingredients: Sertraline)
GINSENG, PANAX (also known as: Korean Ginseng)
NEW ZEALAND GREEN-LIPPED MUSSEL (also known as: Green Lipped Mussel)Natural Product/Drug Interaction Results:
No known interactions were found for the selected products.
Zoloft <<interacts with>> VALERIAN
Interaction Rating = Moderate Be cautious with this combination.
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CYTOCHROME P450 3A4 (CYP3A4) SUBSTRATES
Interaction Rating = Moderate Be cautious with this combination.
Severity = Moderate Occurrence = Possible Level of Evidence = D
There is preliminary evidence that valerian might inhibit the cytochrome P450 3A4 (CYP3A4) enzyme (6450,12214). However, clinical research suggests that valerian might not significantly inhibit CYP3A4 at relatively low doses of 375 mg/day, but might have modest effect at higher doses of 1000 mg/day (13014,13536). Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), and numerous others. Use valerian cautiously or avoid in patients taking these drugs.Source :
poster:nolvas
thread:931595
URL: http://www.dr-bob.org/babble/alter/20091202/msgs/933566.html